van der Laan, Jan Willem: шукати на сайті Z-Library

Critical Reviews in Toxicology

Рік:

2015

Мова:

english

Файл:

PDF, 1.63 MB

english, 2015

Is current risk assessment of non-genotoxic carcinogens protective?

Braakhuis, Hedwig M., Slob, Wout, Olthof, Evelyn D., Wolterink, Gerrit, Zwart, Edwin P., Gremmer, Eric R., Rorije, Emiel, van Benthem, Jan, Woutersen, Ruud, van der Laan, Jan Willem, Luijten, Mirjam

Журнал:

Рік:

2018

Мова:

english

Файл:

PDF, 1.29 MB

english, 2018

An interspecies comparison of placental antibody transfer: New insights into developmental toxicity testing of monoclonal antibodies

Nele Pentšuk, Jan Willem van der Laan

Журнал:

Birth Defects Research Part B: Developmental and Reproductive Toxicology

Рік:

2009

Мова:

english

Файл:

PDF, 214 KB

english, 2009

Assessing immunotoxicity: guidelines

Jan Willem van der Laan, Henk van Loveren

Журнал:

Fundamental & Clinical Pharmacology

Рік:

2005

Мова:

english

Файл:

PDF, 49 KB

english, 2005

Animal models in influenza vaccine testing

van der Laan, Jan Willem, Herberts, Carla, Lambkin-Williams, Robert, Boyers, Alison, Mann, Alexander J, Oxford, John

Журнал:

Expert Review of Vaccines

Рік:

2008

Мова:

english

Файл:

PDF, 232 KB

english, 2008

Adjuvants enhancing an integral immune response to antigens

van der Laan, Jan Willem

Журнал:

Expert Review of Vaccines

Рік:

2005

Мова:

english

Файл:

PDF, 67 KB

english, 2005

Current status and opportunities for therapeutic drug monitoring in the treatment of tuberculosis

Zuur, Marlanka A., Bolhuis, Mathieu S., Anthony, Richard, den Hertog, Alice, van der Laan, Tridia, Wilffert, B., de Lange, Wiel, van Soolingen, Dick, Alffenaar, Jan-Willem C.

Журнал:

Expert Opinion on Drug Metabolism & Toxicology

Рік:

2016

Мова:

english

Файл:

PDF, 841 KB

english, 2016

Quality of Life and Mortality after Endovascular, Surgical, or Conservative Treatment of Elderly Patients Suffering from Critical Limb Ischemia

Steunenberg, Stijn L., de Vries, Jolanda, Raats, Jelle W., Thijsse, Willem J., Verbogt, Nathalie, Lodder, Paul, van Eijck, Geert-Jan, Veen, Eelco J., de Groot, Hans G.W., Ho, Gwan H., van der Laan, Li

Журнал:

Annals of Vascular Surgery

Рік:

2018

Мова:

english

Файл:

PDF, 436 KB

english, 2018

Shared Learnings on the New EMA First-in-Human and Early Clinical Trial Guideline: Proceedings From a DIAlogue Session at DIA Europe 2018

van der Laan, Jan Willem, Benson, Charles T., Janssens, Walter, Bos, Jeroen, Stahl, Elke, Brady, Joseph T., WÃ¤ndel-Liminga, Ulla, Corriol-Rohou, Solange, Forster, Roy, Hartmann, Andreas, Pertel, Pete

Журнал:

Therapeutic Innovation & Regulatory Science

Рік:

2020

Мова:

english

Файл:

PDF, 248 KB

english, 2020

Towards a mechanism-based approach for the prediction of nongenotoxic carcinogenic potential of agrochemicals

Heusinkveld, Harm, Braakhuis, Hedwig, Gommans, Robin, Botham, Phil, Corvaro, Marco, van der Laan, Jan Willem, Lewis, Dick, Madia, Federica, Manou, Irene, Schorsch, FrÃ©dÃ©ric, Wolterink, Gerrit, Woute

Журнал:

Critical Reviews in Toxicology

Рік:

2020

Файл:

PDF, 3.09 MB

2020

Therapy evaluation of laryngeal carcinomas by tyrosine-pet

Jurjan R. de Boer, Jan Pruim, Fred Burlage, Allard Krikke, Anton T. M. G. Tiebosch, Frans W. J. Albers, Willem Vaalburg, Bernard F. A. M. van der Laan

Журнал:

Head & Neck

Рік:

2003

Мова:

english

Файл:

PDF, 132 KB

english, 2003

Carbon-11 tyrosine PET for visualization and protein synthesis rate assessment of laryngeal and hypopharyngeal carcinomas

Jurjan R. de Boer, Bernard F. van der Laan, Jan Pruim, Tjin H. Que, Fred Burlage, Allard Krikke, Antoon T. Willemsen, Anton T. Tiebosch, Frans W. Albers, Willem Vaalburg

Журнал:

European Journal of Nuclear Medicine and Molecular Imaging

Рік:

2002

Мова:

english

Файл:

PDF, 54 KB

english, 2002

Functional analysis of CD4+ CD25bright T cells in kidney transplant patients: improving suppression of donor-directed responses after transplantation

Varsha D.K.D. Sewgobind, Luc J.W. Van Der Laan, Mariska Klepper, Jan N.M. IJzermans, Huug W. Tilanus, Willem Weimar, Carla C. Baan

Журнал:

Clinical Transplantation

Рік:

2008

Мова:

english

Файл:

PDF, 227 KB

english, 2008

Detection of unknown primary tumours and distant metastases in patients with cervical metastases: value of FDG-PET versus conventional modalities

Regelink, Gerreke, Brouwer, Jolijn, de Bree, Remco, Pruim, Jan, van der Laan, Bernard, Vaalburg, Willem, Hoekstra, Otto, Comans, Emile, Vissink, Arjan, Leemans, Ren&#x000E9,

Журнал:

European Journal of Nuclear Medicine and Molecular Imaging

Рік:

2002

Мова:

english

Файл:

PDF, 58 KB

english, 2002

Dopaminertic and α1-adrenergic properties of B-HT920 revealed in morphine-dependent rats

Jan Willem Van der Laan

Журнал:

Pharmacology Biochemistry and Behavior

Рік:

1987

Мова:

english

Файл:

PDF, 450 KB

english, 1987

Effect of chronic prenatal morphine treatment on μ-opioid receptor-regulated adenylate cyclase activity and neurotransmitter release in rat brain slices

Taco J. De Vries, Bernard J. Van Vliet, François Hogenboom, George Wardeh, Jan Willem Van der Laan, Arie H. Mulder, Anton N.M. Schoffelmeer

Журнал:

European Journal of Pharmacology: Molecular Pharmacology

Рік:

1991

Мова:

english

Файл:

PDF, 763 KB

english, 1991

S21: European view of preventing chronic risk from biologics

Experimental and Toxicologic Pathology

Журнал:

Рік:

2009

Мова:

english

Файл:

PDF, 48 KB

english, 2009

Current status and burning issues in immunotoxicity testing of drugs

Jan Willem van der Laan, Henk van Loveren

Журнал:

Toxicology and Applied Pharmacology

Рік:

2005

Мова:

english

Файл:

PDF, 104 KB

english, 2005

The RETHINK project: Minipigs as models for the toxicity testing of new medicines and chemicals: an impact assessment

Roy Forster, Gerd Bode, Lars Ellegaard, Jan Willem van der Laan

Журнал:

Journal of Pharmacological and Toxicological Methods

Рік:

2010

Мова:

english

Файл:

PDF, 149 KB

english, 2010

Regulatory acceptability of the minipig in the development of pharmaceuticals, chemicals and other products

Jan Willem van der Laan, John Brightwell, Peter McAnulty, Joszef Ratky, Claudia Stark

Журнал:

Journal of Pharmacological and Toxicological Methods

Рік:

2010

Мова:

english

Файл:

PDF, 293 KB

english, 2010

The RETHINK project on minipigs in the toxicity testing of new medicines and chemicals: Conclusions and recommendations

Roy Forster, Gerd Bode, Lars Ellegaard, Jan-Willem van der Laan

Журнал:

Journal of Pharmacological and Toxicological Methods

Рік:

2010

Мова:

english

Файл:

PDF, 214 KB

english, 2010

Testing strategies for embryo-fetal toxicity of human pharmaceuticals. Animal models vs. in vitro approaches: A workshop report

Jan Willem van der Laan, Robert E. Chapin, Bert Haenen, Abigail C. Jacobs, Aldert Piersma

Журнал:

Jan Willem van der Laan, Eric de Waal

Рік:

2012

Мова:

english

Файл:

PDF, 255 KB

english, 2012

O XIX C.1 - O XIX C.1 Moving away from a two species requirement for carcinogenicity studies: A regulatory perspective

Журнал:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Рік:

1997

Мова:

english

Файл:

PDF, 128 KB

english, 1997

Mechanisms of Nongenotoxic Carcinogenesis and Assessment of the Human Hazard

Beatriz Silva Lima, Jan Willem Van der Laan

Журнал:

Jan-Willem van der Laan, Per Spindler

Рік:

2000

Мова:

english

Файл:

PDF, 88 KB

english, 2000

The in Vivo Rodent Test Systems for Assessment of Carcinogenic Potential

Журнал:

Willem Den Otter, Peter A. Steerenberg, Jan Willem Van der Laan

Рік:

2002

Мова:

english

Файл:

PDF, 74 KB

english, 2002

Testing Therapeutic Potency of Anticancer Drugs in Animal Studies: A Commentary

Журнал:

Dick Hoekstra, Jan Willem van der Laan, Loe de Leij, Bernard Witholt

Рік:

2002

Мова:

english

Файл:

PDF, 95 KB

english, 2002

Release of outer membrane fragments from normally growing Escherichia coli

Журнал:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Рік:

1976

Мова:

english

Файл:

PDF, 775 KB

english, 1976

Effects of inhibitors of GABA-transaminase on hole-board exploration and on temperature: Relation with effects on quasi-morphine abstinence behaviour induced by sodium dipropylacetate

Jan Willem van der Laan, Gradus Weick, Grada van Bleek

Журнал:

Biochemical Pharmacology

Рік:

1985

Мова:

english

Файл:

PDF, 664 KB

english, 1985

The effects of centrally acting adrenergic agonists on temperature and on explorative and motor behaviour. Relation with effects on quasi-morphine withdrawal behaviour

Jan W. Van Der Laan, Willem Van Veenendaal, Paul Voorthuis, Gradus Weick, Feddo C. Hillen

Журнал:

European Journal of Pharmacology

Рік:

1985

Мова:

english

Файл:

PDF, 451 KB

english, 1985

Dipropylacetate-induced shaking behaviour in the rat: a role of spinal α2-adrenoceptors

Jan Willem Van der Laan, Ris Dirksen

Журнал:

European Journal of Pharmacology

Рік:

1988

Мова:

english

Файл:

PDF, 665 KB

english, 1988

In vitro cytokine release assays for predicting cytokine release syndrome: The current state-of-the-science. Report of a European Medicines Agency Workshop

Jean-Marc Vidal, Thomas T. Kawabata, Robin Thorpe, Beatriz Silva-Lima, Karin Cederbrant, Stephen Poole, Jan Mueller-Berghaus, Marc Pallardy, Jan-Willem Van der Laan

Журнал:

Cytokine

Рік:

2010

Мова:

english

Файл:

PDF, 147 KB

english, 2010

WHO informal consultation on scientific basis for regulatory evaluation of candidate human vaccines from plants, Geneva, Switzerland, 24–25 January 2005

Jan Willem van der Laan, Philip Minor, Richard Mahoney, Charles Arntzen, Jinho Shin, David Wood

Журнал:

Jan G.C. van Amsterdam, Jan-Dirk te Biesebeek, Ton van de Kuil, Jan-Willem van der Laan, Johan Wemer, Dick J. de Wildt, Wim Vleeming

Рік:

2006

Мова:

english

Файл:

PDF, 116 KB

english, 2006

The effect of pertussis toxin and whole-cell pertussis vaccine on haemodynamics and autonomic responsiveness in the rat depends on route of administration and age

Журнал:

Jan G.C. van Amsterdam, Jan-Dirk te Biesebeek, Ton van de Kuil, Jan-Willem van der Laan, Dick J. de Wildt, Wim Vleeming

Рік:

1998

Мова:

english

Файл:

PDF, 768 KB

english, 1998

Repeated administration of whole-cell and acellular pertussis vaccines affects haemodynamics and autonomic responsiveness

Журнал:

Taco J. De Vries, Guno H.K. Tjon Tien Ril, Jan Willem Van der Laan, Arie H. Mulder, Anton N.M. Schoffelmeer

Рік:

1998

Мова:

english

Файл:

PDF, 872 KB

english, 1998

Chronic exposure to morphine and naltrexone induces changes in catecholaminergic neurotransmission in rat brain without altering μ-opioid receptor sensitivity

Журнал:

Life Sciences

Рік:

1993

Мова:

english

Файл:

PDF, 612 KB

english, 1993

Oseltamivir and breastfeeding

Netteke Wentges-van Holthe, Marion van Eijkeren, Jan Willem van der Laan

Журнал:

International Journal of Infectious Diseases

Рік:

2008

Мова:

english

Файл:

PDF, 90 KB

english, 2008

Testing strategies for assessment of carcinogenic risk of drugs: Current developments

Jan Willem Van der Laan

Журнал:

Рік:

2007

Мова:

english

Файл:

PDF, 72 KB

english, 2007

Regulatory view on the relevance of the TDAR in immunotoxicity testing

Jan-Willem van der Laan

Журнал:

Рік:

2009

Мова:

english

Файл:

PDF, 54 KB

english, 2009

New perspectives for alternative approaches to carcinogenicity testing: a regulator viewpoint

Журнал:

Рік:

1998

Мова:

english

Файл:

PDF, 63 KB

english, 1998

W8/L3 - New perspectives for alternative approaches to carcinogenicity testing: A regulator viewpoint

Журнал:

Рік:

1998

Мова:

english

Файл:

PDF, 242 KB

english, 1998

Current status and use of short/medium-term models for assessment of carcinogenicity of human pharmaceuticals: regulatory perspectives

Журнал:

Рік:

2000

Мова:

english

Файл:

PDF, 67 KB

english, 2000

[AAPS Advances in the Pharmaceutical Sciences Series] Global Approach in Safety Testing Volume 5 || Toxicokinetics: A Guidance for Assessing Systemic Exposure in Toxicology Studies, Where Are We Now; An S3A/S3B Update (1995–2011)

Рік:

2013

Мова:

english

Файл:

PDF, 582 KB

english, 2013

[AAPS Advances in the Pharmaceutical Sciences Series] Global Approach in Safety Testing Volume 5 || The Value and Benefits of the International Conference on Harmonisation (ICH) to Drug Regulatory Authorities: Advancing Harmonization for Better Public Health

Рік:

2013

Мова:

english

Файл:

PDF, 109 KB

english, 2013

[AAPS Advances in the Pharmaceutical Sciences Series] Global Approach in Safety Testing Volume 5 || EU Perspective on ICH

Рік:

2013

Мова:

english

Файл:

PDF, 200 KB

english, 2013

[AAPS Advances in the Pharmaceutical Sciences Series] Global Approach in Safety Testing Volume 5 || The International Conference on Harmonisation: History of Safety Guidelines

Рік:

2013

Мова:

english

Файл:

PDF, 199 KB

english, 2013

[AAPS Advances in the Pharmaceutical Sciences Series] Global Approach in Safety Testing Volume 5 || Toward More Scientific Relevance in Carcinogenicity Testing

Рік:

2013

Мова:

english

Файл:

PDF, 344 KB

english, 2013

[AAPS Advances in the Pharmaceutical Sciences Series] Global Approach in Safety Testing Volume 5 || A Japanese Perspective on Implementation of the Three Rs: Incorporating Best Scientific Practices into Regulatory Process

Рік:

2013

Мова:

english

Файл:

PDF, 305 KB

english, 2013

[AAPS Advances in the Pharmaceutical Sciences Series] Global Approach in Safety Testing Volume 5 || Why and How Did Reproduction Toxicity Testing Make Its Early Entry into and Rapid Success in ICH?

Рік:

2013

Мова:

english

Файл:

PDF, 555 KB

english, 2013

[AAPS Advances in the Pharmaceutical Sciences Series] Global Approach in Safety Testing Volume 5 || Duration of Acute and Chronic Toxicity Testing in Animals (ICH S4A and S4B)

Рік:

2013

Мова:

english

Файл:

PDF, 425 KB

english, 2013

[AAPS Advances in the Pharmaceutical Sciences Series] Global Approach in Safety Testing Volume 5 || The Evolution, Scientific Reasoning and Use of ICH S2 Guidelines for Genotoxicity Testing of Pharmaceuticals